On the Road to Personalized Medicine: Discovery of Prognostic Combinatorial High-Order Interactions in Breast Cancer
ON THE ROAD TO PERSONALIZED MEDICINE: DISCOVERY OF PROGNOSTIC COMBINATORIAL HIGH-ORDER INTERACTIONS IN BREAST CANCER
In this work, we developed and validated a systematic workflow that incorporates biomarker classifier and our Pattern Discovery EngineTM for accurate biomarker prediction and for the discovery of novel gene associations in search for novel, personalized strategies for combating breast cancer. Higher-order interactions were identified and validated based on published literature. Our methods provide novel insights into gene interaction patterns in breast cancer and deliver candidates for further study.
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